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Publications of interest for January 2010

24 January 2010

HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. Hartkoorn RC et al. Pharmacogenetics and Genomics 2010.

Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals. Rotger M et al. Circ Cardiovas Genet 2009.

Association between HLA-B*4001 and lipodystrophy among HIV-infected patients from Thailand who received a stavudine-containing antiretroviral regimen. Wangsomboonsiri W et al. CID 2010.

Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique. Ciccacci C et al. Pharmacogenomics 2010.

CYP2C19 genetic variants affect nelfinavir pharmacokinetics and virologic response in HIV-1-infected children receiving highly active antiretroviral therapy. Saitoh A et al. JAIDS 2010.

Common genetic variation and the control of HIV-1 in humans. Fellay J et al. PLoS Genet 2009.

Host genetics influences on HIV type-1 disease. Fellay J. Antivir Ther 2009.

A single amino acid difference in human APOBEC3H variants determines HIV-1 vif sensitivity. Zhen A et al. J Virol 2010.