Human MLH3(MutL Homolog 3) ELISA Kit

Human MLH3(MutL Homolog 3) ELISA Kit

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Human MutL Homolog 3 (MLH3) ELISA Kit
EKN50428-96T 96T
EUR 543.3
Human MutL Homolog 3 (MLH3) ELISA Kit
EKU09317-48T 48T
EUR 610.82
Human MutL Homolog 3 (MLH3) ELISA Kit
EKU09317-5x96T 5x96T
EUR 4144.85
Human MutL Homolog 3 (MLH3) ELISA Kit
EKU09317-96T 96T
EUR 872.6
ELISA kit for Human MLH3 (MutL Homolog 3)
ELK7522 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of MutL Homolog 3 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Human MutL Homolog 3 (MLH3) CLIA Kit
20-abx495965
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
MutL Homolog 3 (MLH3) Antibody
abx146077-100ug 100 ug
EUR 469.2
MutL Homolog 3 (MLH3) Antibody
20-abx324670
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug
MutL Homolog 3 (MLH3) Antibody
abx331047-100ul 100 ul
EUR 510
MutL Homolog 3 (MLH3) Antibody
20-abx014047
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg
MutL Homolog 3 (MLH3) Antibody
abx432972-200ul 200 ul
EUR 343.2
MutL Homolog 3 (MLH3) Antibody
20-abx006534
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
Human MLH1(MutL Homolog 1) ELISA Kit
ELK4307-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MLH1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MLH1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human MLH1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human MLH1 in the samples is then determined by comparing the OD of the samples to the standard curve.
Human MLH1(MutL Homolog 1) ELISA Kit
ELK4307-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MLH1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MLH1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human MLH1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human MLH1 in the samples is then determined by comparing the OD of the samples to the standard curve.
Mlh3 (GFP-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3)
MG211974 10 µg Ask for price
Mlh3 (untagged) - Mouse mutL homolog 3 (E coli) (Mlh3), (10ug)
MC224412 10 µg Ask for price
MLH3 (untagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2
SC127828 10 µg Ask for price
MLH3 (untagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1
SC310948 10 µg Ask for price
MutL Homolog 3 (MLH3) Magnetic Luminex Assay Kit
LKU606805-96T 96T
EUR 1062.6
Human MutL Homolog 1 ELISA Kit (MLH1)
RK01858 96 Tests
EUR 625.2
MLH3 (GFP-tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2
RG212150 10 µg Ask for price
MLH3 (GFP-tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1
RG221591 10 µg Ask for price
Mlh3 (Myc-DDK-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3)
MR211974 10 µg Ask for price
Human MutL Homolog 1 (MLH1) ELISA Kit
20-abx152407
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
Human MutL Homolog 1 (MLH1) ELISA Kit
DLR-MLH1-Hu-48T 48T
EUR 620.4
Description: A sandwich quantitative ELISA assay kit for detection of Human MutL Homolog 1 (MLH1) in samples from tissue homogenates, cell lysates or other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
DLR-MLH1-Hu-96T 96T
EUR 807.6
Description: A sandwich quantitative ELISA assay kit for detection of Human MutL Homolog 1 (MLH1) in samples from tissue homogenates, cell lysates or other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
SEJ742Hu-1x48wellstestplate 1x48-wells test plate
EUR 572.76
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human MutL Homolog 1 (MLH1) in tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
SEJ742Hu-5x96wellstestplate 5x96-wells test plate
EUR 3090.6
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human MutL Homolog 1 (MLH1) in tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
4-SEJ742Hu
  • EUR 5738.40
  • EUR 3031.20
  • EUR 768.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human MutL Homolog 1 (MLH1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.
Human MutL Homolog 1 (MLH1) ELISA Kit
EKU06045-48T 48T
EUR 555.66
Human MutL Homolog 1 (MLH1) ELISA Kit
EKU06045-5x96T 5x96T
EUR 3770.55
Human MutL Homolog 1 (MLH1) ELISA Kit
EKU06045-96T 96T
EUR 793.8
Human MutL Homolog 1 (MLH1) ELISA Kit
EKN47156-48T 48T
EUR 378.7
Human MutL Homolog 1 (MLH1) ELISA Kit
EKN47156-5x96T 5x96T
EUR 2569.75
Human MutL Homolog 1 (MLH1) ELISA Kit
EKN47156-96T 96T
EUR 541
Human MutL Homolog 1 (MLH1) ELISA Kit
RD-MLH1-Hu-48Tests 48 Tests
EUR 625.2
Human MutL Homolog 1 (MLH1) ELISA Kit
RD-MLH1-Hu-96Tests 96 Tests
EUR 867.6
Human MutL Homolog 1 (MLH1) ELISA Kit
RDR-MLH1-Hu-48Tests 48 Tests
EUR 652.8
Human MutL Homolog 1 (MLH1) ELISA Kit
RDR-MLH1-Hu-96Tests 96 Tests
EUR 907.2
Human MutL Homolog 1 (MLH1) ELISA Kit
DL-MLH1-Hu 96T
EUR 441
Description: tissue homogenates, cell lysates or other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
DLR-MLH1-Hu 96T
EUR 463
Description: tissue homogenates, cell lysates or other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
SEJ742Hu-10x96wellstestplate 10x96-wells test plate
EUR 5677.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human MutL Homolog 1 (MLH1) in tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
SEJ742Hu-1x96wellstestplate 1x96-wells test plate
EUR 766.8
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human MutL Homolog 1 (MLH1) in tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
RDR-MLH1-Hu-48T 48T
EUR 475.34
Description: tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
RDR-MLH1-Hu-96T 96T
EUR 679.04
Description: tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
RD-MLH1-Hu-48T 48T
EUR 452.7
Description: tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
RD-MLH1-Hu-96T 96T
EUR 646.7
Description: tissue homogenates, cell lysates and other biological fluids.
Human MutL Homolog 1 (MLH1) ELISA Kit
EK15463 96Т
EUR 768
Mlh3 (untagged ORF) - Rat mutL homolog 3 (E. coli) (Mlh3), (10 ug)
RN209710 10 µg Ask for price
ELISA kit for Human MLH1 (MutL Homolog 1)
ELK4307 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of MutL Homolog 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2
RC212150 10 µg Ask for price
MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1
RC221591 10 µg Ask for price
Mlh3 (Myc-DDK-tagged ORF) - Rat mutL homolog 3 (E. coli) (Mlh3), (10 ug)
RR209710 10 µg Ask for price
Lenti ORF clone of Mlh3 (mGFP-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3)
MR211974L4 10 µg Ask for price
ELISA Kit for MutL Homolog 1 (MLH1)
SEJ742Hu 96Т
EUR 700
Lenti-ORF clone of MLH3 (mGFP-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1
RC221591L4 10 µg Ask for price
Lenti ORF clone of Mlh3 (Myc-DDK-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3)
MR211974L3 10 µg Ask for price
Lenti-ORF clone of MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1
RC221591L3 10 µg Ask for price
Human MutL Homolog 1 (MLH1) CLIA Kit
20-abx495774
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
Lenti ORF particles, Mlh3 (GFP-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3), 200ul, >10^7 TU/mL
MR211974L4V 200 µl Ask for price
Lenti ORF particles, MLH3 (mGFP-tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, 200ul, >10^7 TU/mL
RC212150L4V 200 µl Ask for price
Lenti ORF particles, MLH3 (mGFP-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1, 200ul, >10^7 TU/mL
RC221591L4V 200 µl Ask for price
MLH1 (MutL Homolog 1)
MO47010 100 ul
EUR 418.8
Human MutL Homolog 1 (MLH1) Protein
20-abx654421
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
Lenti ORF particles, Mlh3 (Myc-DDK-tagged) - Mouse mutL homolog 3 (E coli) (Mlh3), 200ul, >10^7 TU/mL
MR211974L3V 200 µl Ask for price
Lenti ORF particles, MLH3 (Myc-DDK tagged) - Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, 200ul, >10^7 TU/mL
RC212150L3V 200 µl Ask for price
Lenti ORF particles, MLH3 (Myc-DDK-tagged)-Human mutL homolog 3 (E. coli) (MLH3), transcript variant 1, 200ul, >10^7 TU/mL
RC221591L3V 200 µl Ask for price
Lenti ORF clone of Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, mGFP tagged
RC212150L4 10 µg Ask for price
Human MutL Homolog 1 ELISA Kit
IHUMLH1KT each
EUR 733
Description: Human MutL Homolog 1 ELISA Kit
Lenti ORF clone of Human mutL homolog 3 (E. coli) (MLH3), transcript variant 2, Myc-DDK-tagged
RC212150L3 10 µg Ask for price
MutL Homolog 1 (MLH1) Antibody
20-abx317973
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
MutL Homolog 1 (MLH1) Antibody
20-abx241566
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul
MutL Homolog 1 (MLH1) Antibody
20-abx241567
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul
MutL Homolog 1 (MLH1) Antibody
abx235213-100ug 100 ug
EUR 577.2
MutL Homolog 1 (MLH1) Antibody
20-abx173641
  • EUR 1028.40
  • EUR 526.80
  • 1 mg
  • 200 ug
MutL Homolog 1 (MLH1) Antibody
20-abx177638
  • EUR 1446.00
  • EUR 693.60
  • 1 mg
  • 200 ug
MutL Homolog 1 (MLH1) Antibody
20-abx113897
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul
MutL Homolog 1 (MLH1) Antibody
abx026385-400ul 400 ul
EUR 627.6
MutL Homolog 1 (MLH1) Antibody
abx026385-80l 80 µl
EUR 343.2
MutL Homolog 1 (MLH1) Antibody
abx025515-100ul 100 ul
EUR 627.6
MutL Homolog 1 (MLH1) Antibody
20-abx014046
  • EUR 376.80
  • EUR 117.60
  • EUR 477.60
  • EUR 142.80
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 20 ug
  • 300 µg
MutL Homolog 1 (MLH1) Antibody
20-abx328114
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug
MutL Homolog 1 (MLH1) Antibody
20-abx002899
  • EUR 493.20
  • EUR 710.40
  • 100 ul
  • 200 ul
MutL Homolog 1 (MLH1) Antibody
20-abx008989
  • EUR 360.00
  • EUR 526.80
  • EUR 226.80
  • 100 ul
  • 200 ul
  • 30 ul
MutL Homolog 1 (MLH1) Antibody
20-abx000639
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
MutL Homolog 1 (MLH1) Antibody
abx012221-100ul 100 ul
EUR 493.2
MLH1 Antibody / MutL Homolog 1
V8749-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V8749-20UG 20 ug
EUR 153.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V8749SAF-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9166-100UG 100ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9166-20UG 20ug
EUR 153.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9166SAF-100UG 100ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2). Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9349-100UG 100ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9349-20UG 20ug
EUR 153.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V9349SAF-100UG 100ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V4038-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V4038-20UG 20 ug
EUR 153.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
MLH1 Antibody / MutL Homolog 1
V4038SAF-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 83kDa, identified as MLH1. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2 (HNPCC2).Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. It introduces single-strand breaks near the mismatch and thus generates new entry points for the exonuclease EXO1 to degrade the strand containing the mismatch. DNA methylation would prevent cleavage and therefore assure that only the newly mutated DNA strand is going to be corrected. MutL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. Also implicated in DNA damage signaling, a process, which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. Heterodimerizes with MLH3 to form MutL gamma, which plays a role in meiosis.
Recombinant MutL Homolog 1 (MLH1)
RPJ742Hu01 10ug
EUR 140
Recombinant MutL Homolog 1 (MLH1)
RPJ742Hu02 10ug
EUR 143
Recombinant MutL Homolog 1 (MLH1)
RPJ742Hu03 10ug
EUR 144
MLH1 (MutL Homolog 1)(MLH1/1324), 0.2mg/mL
BNUB1324-100 1uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), 0.2mg/mL
BNUB1324-500 1uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), 1mg/mL
BNUM1324-50 1uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MutL Homolog 1 (MLH1) Antibody (HRP)
20-abx313263
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
MutL Homolog 1 (MLH1) Antibody (FITC)
20-abx313264
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
MutL Homolog 1 (MLH1) Magnetic Luminex Assay Kit
LKU606804-96T 96T
EUR 966
MutL Homolog 1 (MLH1) Antibody (Biotin)
20-abx313265
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug
MLH1 (MutL Homolog 1)(MLH1/1324), CF647 conjugate, 0.1mg/mL
BNC471324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF647 conjugate, 0.1mg/mL
BNC471324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF568 conjugate, 0.1mg/mL
BNC681324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF568 conjugate, 0.1mg/mL
BNC681324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF594 conjugate, 0.1mg/mL
BNC941324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF594 conjugate, 0.1mg/mL
BNC941324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF640R conjugate, 0.1mg/mL
BNC401324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF640R conjugate, 0.1mg/mL
BNC401324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF488A conjugate, 0.1mg/mL
BNC881324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF488A conjugate, 0.1mg/mL
BNC881324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF405S conjugate, 0.1mg/mL
BNC041324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), CF405S conjugate, 0.1mg/mL
BNC041324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), Biotin conjugate, 0.1mg/mL
BNCB1324-100 1uL
EUR 192
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
MLH1 (MutL Homolog 1)(MLH1/1324), Biotin conjugate, 0.1mg/mL
BNCB1324-500 1uL
EUR 532
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

Human MLH3(MutL Homolog 3) ELISA Kit