Mouse SORT1(Sortilin 1) ELISA Kit

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Sortilin 1 (SORT1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Quantitativesandwich ELISA kit for measuring Mouse Sortilin (SORT1) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Description: Quantitativesandwich ELISA kit for measuring Mouse Sortilin(SORT1) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Description: A sandwich ELISA kit for detection of Sortilin 1 from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Sortilin 1 (SORT1) in tissue homogenates, cell lysates and other biological fluids.

Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Sortilin 1 (SORT1) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Description: Recombinant Mouse Sortilin 1 expressed in: 293F cell

Description: Recombinant Human Sortilin 1 expressed in: E.coli

Description: Quantitativesandwich ELISA kit for measuring Human Sortilin (SORT1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Description: Quantitativesandwich ELISA kit for measuring Human Sortilin(SORT1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Description: Recombinant Rat Sortilin(Sort1),partial expressed in Yeast

Description: Recombinant Rat Sortilin(Sort1),partial expressed in E.coli

Description: Recombinant Rat Sortilin(Sort1),partial expressed in E.coli

Description: A sandwich ELISA kit for detection of Sortilin 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Description: A sandwich ELISA kit for quantitative measurement of Human SORT1 (Sortilin 1) in samples from Serum, Plasma, Cell supernatant

Description: Quantitative sandwich ELISA for measuring Rat Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Rat Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: Quantitative sandwich ELISA for measuring Human Sortilin (SORT1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1)

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with APC.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with Biotin.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with HRP.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with Cy3.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with FITC.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with PE.

Description: A Rabbit polyclonal antibody against Human, Pig Sortilin 1 (SORT1). This antibody is labeled with APC-Cy7.

Description: Description of target: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.066 ng/mL

Description: Description of target: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 1.56 pg/mL

Description: Description of target: ;Species reactivity: Mouse;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.066 ng/mL

Description: A sandwich ELISA for quantitative measurement of Mouse Sortilin related receptor(SORL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Mouse Sortilin related receptor(SORL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: A sandwich ELISA for quantitative measurement of Mouse Sortilin related receptor(SORL1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Description: Description of target: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.10 Publications <p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment iniRef.10"Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase."_x005F_x005F_x000D_Nielsen M.S., Jacobsen C., Olivecrona G., Gliemann J., Petersen C.M._x005F_x005F_x000D_J. Biol. Chem. 274:8832-8836(1999) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.11"The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein."_x005F_x005F_x000D_Nielsen M.S., Madsen P., Christensen E.I., Nykjaer A., Gliemann J., Kasper D., Pohlmann R., Petersen C.M._x005F_x005F_x000D_EMBO J. 20:2180-2190(2001) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH GGA2, MUTAGENESIS OF TYR-792; LEU-795 AND 829-LEU-LEU-830.Ref.12"Golgi-localizing, gamma-adaptin ear homology domain, ADP-ribosylation factor-binding (GGA) proteins interact with acidic dileucine sequences within the cytoplasmic domains of sorting receptors through their Vps27p/Hrs/STAM (VHS) domains."_x005F_x005F_x000D_Takatsu H., Katoh Y., Shiba Y., Nakayama K._x005F_x005F_x000D_J. Biol. Chem. 276:28541-28545(2001) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH GGA1 AND GGA2, MUTAGENESIS OF 823-ASP-ASP-824; SER-825; 826-ASP--ASP-828 AND 829-LEU-LEU-830.Ref.14"Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization."_x005F_x005F_x000D_Maeda S., Nobukuni T., Shimo-Onoda K., Hayashi K., Yone K., Komiya S., Inoue I._x005F_x005F_x000D_J. Cell. Physiol. 193:73-79(2002) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INDUCTION.Ref.16"The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin."_x005F_x005F_x000D_Lefrancois S., Zeng J., Hassan A.J., Canuel M., Morales C.R._x005F_x005F_x000D_EMBO J. 22:6430-6437(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH GM2A AND PSAP, SUBCELLULAR LOCATION.Ref.17"Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia."_x005F_x005F_x000D_Martin S., Vincent J.-P., Mazella J._x005F_x005F_x000D_J. Neurosci. 23:1198-1205(2003) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION.Ref.18"Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells."_x005F_x005F_x000D_Morinville A., Martin S., Lavallee M., Vincent J.-P., Beaudet A., Mazella J._x005F_x005F_x000D_Int. J. Biochem. Cell Biol. 36:2153-2168(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, SUBCELLULAR LOCATION.Ref.20"Sortilin is essential for proNGF-induced neuronal cell death."_x005F_x005F_x000D_Nykjaer A., Lee R., Teng K.K., Jansen P., Madsen P., Nielsen M.S., Jacobsen C., Kliemannel M., Schwarz E., Willnow T.E., Hempstead B.L., Petersen C.M._x005F_x005F_x000D_Nature 427:843-848(2004) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH NGFB AND NGFR.Ref.21"ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin."_x005F_x005F_x000D_Teng H.K., Teng K.K., Lee R., Wright S., Tevar S., Almeida R.D., Kermani P., Torkin R., Chen Z.-Y., Lee F.S., Kraemer R.T., Nykjaer A., Hempstead B.L._x005F_x005F_x000D_J. Neurosci. 25:5455-5463(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.22"Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway."_x005F_x005F_x000D_Chen Z.-Y., Ieraci A., Teng H., Dall H., Meng C.-X., Herrera D.G., Nykjaer A., Hempstead B.L., Lee F.S._x005F_x005F_x000D_J. Neurosci. 25:6156-6166(2005) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION, INTERACTION WITH BDNF. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: < 0.064 ng/mL

Description: Description of target: This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ;Assay info: Quantitative Sandwich ELISA;Sensitivity: < 0.061 ng/mL

Description: Description of target: This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.058 ng/mL

Description: Description of target: This gene encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of this gene may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 22.5 pg/mL

Description: Description of target: may be involved in sorting lumenal proteins in the trans-Golgi [RGD, Feb 2006];Species reactivity: Rat;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.054ng/mL

Description: This Human Soluble Sortilin (sSortilin) ELISA Kit contains the necessary components required for the quantitative measurement of recombinant and/or natural human soluble Sortilin (sSortilin) from cell culture supernates and tissue homogenates, serum and p

Description: Quantitative sandwich ELISA for measuring Mouse Sortilin-related receptor (SORL1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.